First Interstate Tower is a name that was carried by several bank buildings of the former First Interstate Bancorp, in the United States, and may refer to:
Aon Center (Los Angeles), California, formerly named First Interstate Tower Wells Fargo Center (Portland, Oregon), formerly named First Interstate Tower Fountain Place, in Dallas, Texas, formerly named First Interstate Tower 621 17th Street, in Denver, Colorado, formerly named First Interstate Tower South 633 17th Street, in Denver, Colorado, formerly named First Interstate Tower North
See also First Interstate Tower fire First Interstate Center (disambiguation)