Epirus is a historical and geographical region of the southwestern Balkans, straddling modern Greece and Albania.

The name Epirus, from the Greek "Ήπειρος" meaning "continent" may also refer to:

Geographical Epirus (region), one of the thirteen regions (administrative divisions) of Greece Northern Epirus, a Greek political term used to refer to parts of southern Albania

Historical Epirus (ancient state), an ancient Greek state (330–167 BC) Epirus Vetus ("Old Epirus", 146 BC–395 AD), province of the Roman Empire Epirus Nova ("New Epirus"), a province of the Roman Empire Despotate of Epirus (1205–1479), one of the successor states of the Byzantine Empire Autonomous Republic of Northern Epirus, a short lived entity (1914) proclaimed by the pro-Greek party in the south of the Principality of Albania

People Epirus (mythology) from Greek mythology, daughter of Echion and Agave

Technology Epirus Leonidas, an anti-drone weapon

See also Eprius, a genus of butterflies