DeLorenzo or De Lorenzo or de Lorenzo is an Italian surname. It may refer to:
Bart DeLorenzo (born 1965), American theater director Dana DeLorenzo (born 1983), American actress Enrico de Lorenzo, Italian bobsleigher who competed during the 1960s Francesco De Lorenzo (born 1938), Italian doctor and politician Giovanni de Lorenzo Larciani (1484-1527), Italian painter Italo de Lorenzo, Italian bobsleigher who competed in the mid-1960s Leonardo De Lorenzo (1875–1962), Italian musician Michael DeLorenzo (born 1959), American actor Tista De Lorenzo (born 1934), Australian football player Victor DeLorenzo (born 1954), American musician
See also De Lorenzo's Tomato Pies, a pizzeria in New Jersey Lorenzo (name)