Route 440 or Highway 440 may refer to:
Australia South Gippsland Highway
Canada Manitoba Provincial Road 440 New Brunswick Route 440 Newfoundland and Labrador Route 440 Quebec Autoroute 440
Japan Route 440 (Japan)
United States Interstate 440 (disambiguation) Arkansas Highway 440 Hawaii Route 440 Louisiana Highway 440 Maryland Route 440 New Jersey Route 440 New York State Route 440 Ohio State Route 440 (former) Puerto Rico Highway 440