Loper is a surname. Notable people with the surname include:
Alonzo A. Loper (1829–1917), American politician Bert Loper (1869–1949), early Grand Canyon river runner Brad Loper (born 1970), American photojournalist Daniel Loper (born 1982), American football offensive tackle David Loper (), American geologist Don Loper (1906–1972), American costume and necktie designer Edward L. Loper, Sr. (1916–2011), African American artist James Loper (1931–2013), American television executive Johnny Loper (), American drag racer Herbert Loper (1896–1989), American general Whitly Loper (born 1986), American sport shooter Ron Loper Jr (born 2007), American rapper/music artist
See also Loper Bright Enterprises v. Raimondo (2024), a US Supreme Court case