Kleopatra is a non-English spelling of Cleopatra. It may also refer to:

Kleopatra (singer) (born 1963), a Greek singer 216 Kleopatra, a triple asteroid orbiting in the asteroid belt Kleopatra (opera), a Danish-language opera by August Enna 1875 Kleopatra, a 2002 musical by Czech singer Michal David "Kleopatra", a song by Fergie from Double Dutchess

See also Cleopatra (disambiguation)