Murtha is a surname. Notable people with the surname include:
Andrew Murtha (born 1965), Australian speed skater John Murtha (1932–2010), member of the United States Congress John Garvan Murtha (born 1941), United States federal judge John Murtha (Wisconsin politician) (born 1951), Wisconsin state assemblyman Lydon Murtha (born 1985), American football player William H. Murtha (1841–1891), merchant and New York politician Tish Murtha (1956–2013), documentary photographer
See also Johnstown–Cambria County Airport, an airport named after the congressman USS John P. Murtha (LPD-26), a US Navy ship named after the congressman Murtagh