Wade Hampton may refer to the following people:
People Wade Hampton I (1752–1835), American soldier in Revolutionary War and War of 1812 and U.S. congressman Wade Hampton II (1791–1858), American plantation owner and soldier in War of 1812 Wade Hampton III (1818–1902), American Civil War soldier and politician; elected Governor and Senator of South Carolina, opponent of Reconstruction William Wade Hampton (1854–1928), Florida lawyer commonly known as Wade Hampton Wade Hampton Frost (1880-1938), professor of epidemiology Wade Randolph Hampton, an American DJ active since the mid-1990s
Places Kusilvak Census Area, Alaska, formerly Wade Hampton Census Area Wade Hampton, South Carolina Wade Hampton Boulevard