San Severino can refer to:

Places in Italy Mercato San Severino, a commune of the Province of Salerno San Severino Lucano, a commune of the Province of Potenza San Severino Marche, a commune in the Province of Macerata San Severino (Centola), a hamlet of Centola in the Province of Salerno Santi Severino e Sossio, Naples, a church in Central Naples, Italy

People Severinus of Noricum, a Roman Catholic saint Severin of Cologne, another saint

See also Sanseverino Severino