Datla is a Telugu surname. Notable people bearing the name include:
Datla Satyanarayana Raju (1904–1973), personal doctor to Netaji Subhash Chandra Bose Datla Balarama Raju (1907–1998), Indian politician, Member of Parliament for Narasapuram from 1962 to 1971 Datla Venkata Suryanarayana Raju (1928–2010), Indian film producer and chairman of the National Film Development Corporation Ramesh Datla, Indian industrialist (born 1961), chairman and managing director of Elico Limited Datla Venkata Krishnam Raj, founder of Biological E. Limited Mahima Datla, managing director of Biological E. Limited