Big Boo may refer to:

Big Boo, a larger and stronger version of Boo in the Mario franchise Carrie "Big Boo" Black, a character in the television series Orange Is the New Black (2013) "Big Boo", a character in the television series Sunny Bunnies (2015)

See also Boo (disambiguation) Big Bad Boo, Canadian production company Big Bam Boo, 1980s British pop/rock duo Boo Boo (disambiguation) "Bug a Boo" (song), a 1999 single by US pop group Destiny's Child