1U may refer to:

ITA Software (IATA code) 1U, a rack unit measurement 1U server; see Pizza box form factor RS-1U, a type of K-5 (missile) J-1U, a model of Auster Workmaster SSH 1U (WA); see Washington State Route 503 An abbreviation for 1 Utama An abbreviation for "One Union" or "One Big Union", a concept and slogan used by industrial unionists, including the IWW. #1U is used also as a hashtag on social media by labor activists and organizations. basic CubeSat size unit

See also U1 (disambiguation)