Pernes may refer to:
Places Pernes, Pas-de-Calais Bailleul-lès-Pernes, Pas-de-Calais La Roque-sur-Pernes, Vaucluse Pernes-lès-Boulogne, Pas-de-Calais Pernes-les-Fontaines, Vaucluse Sains-lès-Pernes, Pas-de-Calais Pernes, a parish in Santarém, Portugal
People Fernando Pernes (1936–2010), Portuguese essayist, professor and art critic Jiří Pernes (1948–2025), Czech historian Thomas Pernes (1956–2018), Austrian avant-garde composer and performance artist
See also Perne, a surname