HSK may refer to:
Sport Helsingfors Segelklubb, a Finnish sailing club Helsingfors Skridskoklubb, a Finnish figure skating club Henderson Silver Knights, an American hockey team Hadsten Sports Klub, a Danish multi-sports club
Transport Hassocks railway station, Sussex, England Hung Shui Kiu station, Hong Kong Hung Shui Kiu stop, Hong Kong Huesca–Pirineos Airport, Aragon, Spain Handels-Stör-Kreuzer, a German auxiliary cruiser
Other uses H. S. Krishnaswamy Iyengar Hanyu Shuiping Kaoshi or Chinese Proficiency Test Homoserine kinase, an enzyme Horrendous Space Kablooie, a Calvin and Hobbes reference to the Big Bang Hohlschaftkegel ("hollow shank taper"), a form of machine taper