Slayer is an American thrash metal band.

Slayer or Slayers may also refer to:

Slayer, an archaic term for murderer Slayer rule, a doctrine prohibiting a murderer to inherit from the victim

People SlayerS 'BoxeR', in-game name of StarCraft player Lim Yo-hwan

Film and TV The Slayer, a 1982 horror film Slayer (film), a 2006 film Slayers (film), a 2022 American horror film Slayer (Buffy the Vampire Slayer), a type of female character, charged with fighting vampires and demons, in the TV series and franchise Buffy the Vampire Slayer

Books and comics Slayers, a Japanese fantasy light novel and media franchise Slayers: A Buffyverse Story, an audiobook written and directed by Amber Benson and Christopher Golden Slayer, a character in The Wheel of Time

Games Slayer (video game), a horizontally scrolling shooter game released in 1988 Slayer (Guilty Gear), a video game character from the fighting game series Guilty Gear Slayer, a character class or skill in various role-playing games Advanced Dungeons & Dragons: Slayer, a 1994 role-playing video game for the 3DO Slayers (video game), a video game based on the Slayers light novel series Slayers (role-playing game), a 2020 tabletop role-playing game Slayers X: Terminal Aftermath: Vengance of the Slayer, a 2023 first-person shooter Lina the Slayer, a heroine in the video game Dota 2

Music S.A. Slayer, formerly Slayer, an American heavy metal band "Slayers", a 1998 song from the Vampires film soundtrack "Slayers", a 2009 song from the Gamer film soundtrack Slayr, rapper and producer

Other uses Washington D.C. Slayers, an American rugby league team

See also Kinslayer (disambiguation), murderer of own family/kin Dragonslayer Slay (disambiguation) S-layer