Semele is the mother of Dionysus in Greek mythology.
Semele may also refer to:
Semele (play), a lost tragedy by Aeschylus Semele (Eccles), an opera by John Eccles Semele (Handel), an opera by George Frideric Handel (given as an oratorio in its first run) Semele (Schiller), a singspiel libretto by Friedrich Schiller Sémélé, an opera by Marin Marais Sémélé (Dukas cantata), a cantata by Paul Dukas 86 Semele, an asteroid Semele (plant), a genus of flowering plants Semele (bivalve), a genus of bivalves Radford Semele, a village in Warwickshire, England