WISC may refer to:
Wechsler Intelligence Scale for Children WISC-TV, a television station (channel 11, virtual 3) licensed to Madison, Wisconsin, United States Wisconsin, short form of Wisconsin Wisconsin Integrally Synchronized Computer Writable instruction set computer Wind and/or infrared sensitive collector, a type of uncovered hybrid photovoltaic/solar thermal collector University of Wisconsin–Madison Wisconsin Supreme Court West Indian Students' Centre, London