U Street or "U" Street is the 22nd of a sequence of alphabetical streets in many cities (or the 21st if "I" or "J" is omitted).

It may refer to: U Street (Washington, D.C.), a street in Washington, D.C. U Street (Washington, D.C.), commercial and residential district in northwest Washington, D.C. U Street station, a Metro station in Washington, D.C. on the Green and Yellow Lines

See also School of Hard Knocks or "University of the Streets" University/65th Street, a station in Sacramento, California Street University, a project of the Ted Noffs Foundation in New South Wales, Australia

Avenue U (disambiguation) University Avenue (disambiguation) University Street (disambiguation)