Gendebien is a surname. Notable people with this surname include:
Alexandre Gendebien (1789–1869), Belgian lawyer and participant in the Belgian Revolution Blake Gendebien, American farmer and Congressional candidate, see 2026 United States House of Representatives elections in New York Olivier Gendebien (1924–1998), Belgian racing driver Paul-Henry Gendebien (1939–2024), Belgian economist and politician