Syncollin is a protein that in humans is encoded by the SYCN gene. This protein is found in the acinar cells of the pancreas, and is involved their secretion of digestive enzymes (via exocytosis). Inside of acinar cells, syncollin is found in the membranes of zymogen granules which contain active and inactive digestive enzymes. It functions to regulate the merging of these granules, but does not appear to be strictly necessary for their formation.
Interactions Synocollin has been found to interact with GP2, a protein secreted by acinar cells which may have an immune function.
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