Thaçi is a surname. Notable people with the surname include:
Adelina Thaçi, Kosovar singer and teacher Bler Thaçi (born 1999), Kosovar football midfielder Hashim Thaçi (born 1969), Kosovar politician and war criminal Ilirjan Thaçi (1995–2012), football defender Menduh Thaçi, North Macedonian politician Muhamed Thaçi (born 1981), North Macedonian-born basketball coach and former player