YANK1, also known as serine/threonine-protein kinase 32A (STK32A), is a protein kinase that in humans is encoded by the STK32A gene.He, Q., Cheng, Y., Zhao, S., Li, Y., Cui, L., Tang, B., Chang, Y., Duan, Q., Zhu, F., & Xiao, J. (2026). Exploring the YANK family: Emerging therapeutic targets for various diseases. Oncology and Translational Medicine, 12(3), 132–144. DOI: https://doi.org/10.1097/ot9.0000000000000139 YANK1 belongs to the yet another novel kinase (YANK) family, which includes YANK1 (serine/threonine kinase 32A), YANK2 (serine/threonine kinase 32B), and YANK3 (serine/threonine kinase 32C). YANK1 currently does not have any identified substrates. YANK1 is known to interact with EMX2, where it regulates the orientation of stereociliary bundles in hair cells of the inner ear by interacting with the PCP signaling pathway.
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