Pachyprosopis holoxanthopus, or Pachyprosopis (Pachyprosopis) holoxanthopus, is a species of bee in the family Colletidae and subfamily Euryglossinae. It is endemic to Australia. It was described by British-American entomologist Theodore Dru Alison Cockerell in 1914.

Distribution and habitat The species occurs in inland eastern Australia. The type locality is Yarrawin, New South Wales. It has also been recorded from Charleville, Queensland.

Behaviour The adults are flying mellivores. Flowering plants visited by the bees include Eucalyptus and Schinus species.

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