Kefer is a surname. Notable people with the surname include:
Franz Xaver Kefer (1763–1802), German educator Jan Kefer (1906–1941), Czech astrologer, hermeticist and publicist Rose Hobart, born Rose Kefer (1906–2000), American actress
See also Portrait of Jeanne Kéfer, 1885 painting by Fernand Khnopff Keefer, a surname Kiefer, a given name and surname