Pucciarelli is an Italian surname. Notable people with the surname include:
Eugenio Pucciarelli (1907–1995), Argentine essayist (1939–2018), Argentine anthropologist Manuel Pucciarelli (born 1991), Italian footballer Nicholas Pucciarelli (1923–1983), American politician Paulus Pucciarelli (1583–1631), Greek bishop Stefania Pucciarelli (born 1967), Italian politician
See also Federico Pucciariello (born 1975), Argentine rugby union player