Francisco Maldonado may refer to:
Francisco Maldonado (rebel) (1480-1521), Spanish leader of the rebel Comuneros Francisco Maldonado (monk) (1571-1650), Guatemalan Franciscan linguist and historian Francisco Maldonado da Silva (1592-1639), Peruvian marrano physician Francisco Severo Maldonado (1775-1832), philosopher, Catholic priest, professor and writer from New Spain Francisco Maldonado (footballer) (born 1943), Peruvian football defender Francisco José Maldonado (born 1981), Spanish football forward