Fusicatenibacter saccharivorans is a species of anoxic, Gram-positive, non-motile bacteria that was first isolated from human faeces. It has a spindle shape and is non-spore-forming. The bacterium ferments glucose to produce lactic acid, formic acid, acetic acid and succinic acid. The type strain of the species is HT03-11(T) ( = YIT 12554(T) = JCM 18507(T) = DSM 26062(T)).
Relationship with intrahepatic cholangiocarcinoma Fusicatenibacter saccharivorans is enriched in fecal samples of patients with intrahepatic cholangiocarcinoma (ICC). Studies in mice suggest that F. saccharivorans can accelerate and facilitate ICC progression by suppressing CD8+ T cells. This is mediated by a protein produced by the bacterium, Pepd.
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