Laffillé (also spelled Laffillée and Lafille) is a surname of French origin meaning 'the daughter' or 'the girl'. Notable people with the surname include:
Lafille
, French Polynesian judoka , Australian freestyle wrestler (born 1988), French judoka
Laffillé Charles Laffillé (1771–1848), French composer Jean-François Laffillé (born 1962), French cyclist Pierre Laffillé (1938–2011), French painter
Laffillée (1859–1947), French architect (1889–1970), French architect