Muriel is a surname. Notable people with the surname include:
Adriana Muriel (), Colombian former racing cyclist Alma Muriel (1951–2014), Mexican actress John Muriel (1909–1975), British countryman, teacher, novelist, and biographer Josefina Muriel (1918–2008), Mexican writer, historian, researcher, bibliophile, and academic Luis Muriel (born 1991), Colombian footballer