McHugo (also McHugho and MacHugo) is an Irish surname. Notable people with this name include:

Edmond MacHugo (alias MacCoug, MacCook, Cook) (alive 1559), Irish Chief of the Name Anthony McHugo (died 1711), Irish cleric, the third and last attested Prior of Portumna Priory James MacHugo, 18th-century Irish merchant Colin McHugo (born 1945), British professional tennis player

McHugo can also refer to McHugo Peak, a mountain in Antarctica.

See also McHugh