Rhyzobius quadrifenestratus is a species of beetle of the family Coccinellidae. It is found in South Africa (Eastern Cape).
Description Adults reach a length of about . They have a broadly oval, moderately convex body. They are yellowish brown with the elytra dark brown along the disc. There are two yellowish brown spots within this dark area. The pubescence on the dorsum consists of appresed setae and some stiff bristles.
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