Rhyzobius apicesignatus is a species of beetle of the family Coccinellidae. It is found in South Africa (Western Cape).

Description Adults reach a length of about . They have an elongate oval, moderately convex body. They are light brown, with the apex of the elytra dark brown with a pale macula within this darker area. The pubescence on the dorsum consists of appresed setae and dark stiff bristles.

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