David R. Williams may refer to: David R. Williams (scientist) (born 1954), Saint Lucian-American public health scientist at Harvard David Robert Williams (1954–2026), American aerospace and mechanical engineer David Rogerson Williams (1776–1830), governor of South Carolina from 1814 to 1816 Dafydd Williams (born 1954), also known as Dafydd "Dave" Rhys Williams, Canadian astronaut