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Setidegrasib

Setidegrasib is an investigational new drug that is being evaluated by Astellas Pharma for the treatment of solid tumors. It is an PROTACs degrader of the KRAS…

Setidegrasib is an investigational new drug that is being evaluated by Astellas Pharma for the treatment of solid tumors. It is an PROTACs degrader of the KRAS protein harboring a G12D mutation.

Clinical trials

Setidegrasib in combination with either FOLFIRINOX or NALIRIFOX chemotherapy is currently in phase 3 clinical trials for the treatment of pancreatic cancer.

References

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