Mirghani or al-Mirghani () can be a given name, a middle name, or a surname. Notable people with the name include:
Given name
Mirghani Alnasri, Sudanee politician Mirghani Al Zain (born 1978), Sudanese-born Qatari football midfielder and coach
Middle name
Mohammed Uthman al-Mirghani al-Khatim (1793–1852), Mecca-born founder of the Khatmiyya sufi tariqa
Surname
Ahmed al-Mirghani (1941–2008), former president of Sudan Ali al-Mirghani (c. 1873 – 1968), Sudanese politician and Islamic leader Ibrahim al-Mirghani (born 1982), Sudanese politician Mohamed Osman al-Mirghani (born 1936), Sudanese politician and Islamic leader Suzannah Mirghani, Qatar-based filmmaker
See also
Al Mirghani ESC, football club based in Kassala, Sudan Al-Mahdi and al-Mirghani rivalry, former sectarian feud in Anglo-Egyptian Sudan