Reine can be a feminine given name or a surname. Notable people with the name include:
Mononym Regina of Autun (), French-born Catholic martyr
Nickname Sixte Coupal dit la Reine, Canadian farmer and political figure
Given name Reine Abbas, Lebanese video game designer and artist Reine Alapini-Gansou, Beninese judge Reine Almqvist (born 1949), Swedish football coach and striker Reine Andersson (1945–2005), Swedish sailor Reine Antier, French Roman Catholic nun Reine Audu, French fruit seller and revolutionary Reine Barkered (born 1982), Swedish big mountain skier Reine Brynolfsson, Swedish actor Reine Davies, American singer and actress Reine Feldt (1945–1986), Swedish football defender and journalist Reine Fiske, Swedish guitarist Reine Flachot, French cellist Reine Gianoli, French classical pianist Reine Hibiki, Japanese illustrator Reine Mazoyer, French plastic artist Reine Arcache Melvin, Filipina-American author Reine Ngotala, Gabonese beauty pageant titleholder Reine Colaço Osorio-Swaab, Dutch composer Reine Sosso (born 1993), Cameroonian football goalkeeper Reine Swart, South African director, writer, and actress Reine Philiberte de Varicourt, French woman of letters Reine Wisell (1941–2022), Swedish racing driver
Surname Paul Reine, Norwegian forester and politician Yannick Reine (born 1987), French kickboxer