Muggleton is a surname of English origin. People with the surname include:
Amanda Muggleton (born 1951), Australian actress Andrew Muggleton (born 1974), English cricketer Brian Muggleton (1941–2022), Australian cricketer Carl Muggleton (born 1968), English footballer John Muggleton (born 1960), Australian rugby league player Josh Muggleton (born 1989), a participant in the British television series Yeardot Lodowicke Muggleton (1609–1698), English religious leader Louis Muggleton (1922–2015), South African born British physicist and engineer Sam Muggleton (born 1995), English footballer Stephen Muggleton (born 1959), British computer scientist