Cyclin-dependent kinase 19 (or CDK19) is an enzyme that in humans is encoded by the CDK19 gene.
Inhibitors
The natural product cortistatin A is a potent and selective inhibitor of CDK8 and CDK19.
Romaciclib is a dual CDK8 and CDK19 inhibitor which is being developed for the treatment of acute myeloid leukaemia (AML).
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