The 1949–1950 Coupe de France was the 33rd edition of the Coupe de France, the primary cup competition in France. It was won by Stade de Reims, who beat RC Paris 2–0 in the final.

Round of 32

!colspan="3" align="center"|Replay

Round of 16

!colspan="3" align="center"|Replay

Quarter-finals

!colspan="3" align="center"|Replay

Semi-finals

Final

References Coupe de France results at Rec.Sport.Soccer Statistics Foundation Report on French federation site