The following is a list of U.S. ambassadors to APEC. The formal title is United States Senior Official for Asia-Pacific Economic Cooperation with the rank of Ambassador during tenure of service. Previously, the role has also been called United States Coordinator for APEC.

List of U.S. Ambassadors to APEC and U.S. Senior Officials for APEC +AmbassadorImageAssumed officeLeft officeSandra J. Kristoff19951996John S. WolfFebruary 19971999Richard A. Boucher19992000C. Lawrence Greenwood20002003Lauren Moriarty20032005Michael W. Michalak20052007Patricia M. HaslachJune 11, 20072009Kurt W. TongSeptember 2009November 2011Atul KeshapJuly 2012August 2013Robert S. WangAugust 20132015Matthew J. MatthewsJune 16, 20152019Sandra OudkirkJuly 6, 2019July 12, 2021Matt MurrayFebruary 2022July 2025Casey MaceAugust 7, 2025present

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