Jean-Adrien is a French masculine given name. Notable people with the name include:
People Jean-Adrien Guignet (1816–1854), French orientalist painter Jean-Adrien Mercier (1899–1995), French illustrator and poster artist
See also Jean Adrien Bigonnet (1755–1832), French politician Jean Adrien Vanovason, Malagasy politician Adrien Philippe (1815–1894; born Jean Adrien Philippe), French watchmaker and businessman Jean Jules Jusserand (1855–1932; Jean Adrien Antoine Jules Jusserand), French author and diplomat Jean Lecanuet (1920–1993; Jean Adrien François Lecanuet), French politician Jean-Marthe-Adrien l'Hermite (1766–1826), French Navy officer Adrien-Jean JA (disambiguation)