Zakim is a surname and a given name. Notable people with the name include:

Zakim Shah (Afghan election official), the chairman of Afghanistan's Joint Election Management Board Zakim Shah (Guantanamo captive 898) Josh Zakim (born 1983), American politician, attorney, and community activist Leonard P. Zakim (1953–1999), Jewish American religious and civil rights leader

See also Leonard P. Zakim Bunker Hill Memorial Bridge across the Charles River in Boston, Massachusetts