The 1941 Wiley Wildcats football team represented Wiley College as a member of the Southwestern Athletic Conference (SWAC) during the 1941 college football season. Led by 19th-year head coach Fred T. Long, the Wildcats compiled an overall record of 1–6–1, with a conference record of 0–5–1, tying for sixth place at the bottom of the SWAC standings.
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