The electron Bio-Imaging Centre (eBIC) is a national facility in the United Kingdom that houses equipment and specialists for structural biology using Cryogenic electron microscopy.
History Opening in 2018, eBIC was established at Diamond Light Source in collaboration with Birkbeck College, Oxford University and Thermo Fisher via a £15.6 million grant from the Wellcome Trust, the Medical Research Council and the Biotechnology and Biological Sciences Research Council.
Activities The Electron Bio Imaging Centre supports Single particle analysis, Cryogenic electron tomography, and Microcrystal electron diffraction.
eBIC's imaging facilities have contibuted to vaccine development, including the Oxford–AstraZeneca COVID-19 vaccine and a polio vaccine using virus-like particles Additionally, their microscopes were used for determining structures of the SARS-CoV-2 spike protein.
The facility also operates an 'eBIC for Industry' centre for industrial users to access specific equipment and expertise, training, or mail-in or full service Single particle structure determination.
Research at eBIC includes electron ptychography, FIB-SEM for Cryogenic electron tomography, and automated collection and data processing.
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