Alpuche is a surname. Notable people with the surname include:

Abraham Alpuche (born 1987), Mexican footballer Celia Mercedes Alpuche Aranda (born 1956), Mexican medical doctor Graciliano Alpuche Pinzón, Governor of Yucatán, Mexico, from 1982 to 1984 José María Alpuche (1780–1840), Mexican priest and politician Wenceslao Alpuche (1804–1841), Mexican poet and politician Yolanda Noemí Alpuche Morales (1929–2012; known as Yolanda Mérida), Mexican actress

See also