The Khuzani family () was an Iranian family active in Isfahan during the 15th–17th centuries. Their family name is derived from village of Khuzan, now located in the Khomeynishahr city near Isfahan. The first member to settle in Khuzan was a certain Shah Mahmud, who had moved from Baghdad in the 1440s.
Other Khuzani members with unknown family origins: Rais Shihab al-Din, Khvajeh Enayatollah, Mirza Enayat ibn Mirza Mo'men.
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