The 1938 Prairie View Panthers football team was an American football team that represented Prairie View State Normal & Industrial College (now known as Prairie View A&M University) as a member of the Southwestern Athletic Conference (SWAC) during the 1938 college football season. In their ninth season under head coach Sam B. Taylor, the Panthers compiled an overall record of 4–2–3, with a mark of 2–2–2 in conference play, and finished third in the SWAC.

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