The 1948 Prairie View A&M Panthers football team was an American football team that represented Prairie View A&M College of Texas (now known as Prairie View A&M University) as a member of the Southwestern Athletic Conference (SWAC) during the 1948 college football season. In their first season under head coach Fred T. Long, the Panthers compiled an overall record of 6–4–1, with a mark of 4–2–1 in conference play, and finished fourth in the SWAC.

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