Mirza Hedayatollah () was a bureaucrat in Safavid Iran, who served as the grand vizier of Mohammad Khodabanda () from 1583 to 1586. Before his promotion, he had served as the mostowfi ol-mamalek (comptroller general) since 1577. After his tenure as grand vizier, he was appointed as the fiscal manager of Isfahan. Under the rule of Shah Abbas I (), the distribution of tuyul (land grants) within the royal camp were overseen by Mirza Hedayatolllah. During Shah Abbas I's pilgrimage to Mashhad in 1601–1602, Mirza Hedayatollah accompanied the royal party and conducted a measurement of the route from Isfahan.
A member of the Khuzani family, Mirza Hedayatollah was a son of Mirza Jan Beg Khuzani. During this period, Mirza Hedayatollah likely acted as the main representative of the family in Isfahan, as his brother Mirza Yar Ahmad Khuzani had moved to Sistan in 1556/57 to serve as the vizier of Badi-al Zaman Mirza Safavi.
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