Manolita is a diminutive form of the Spanish given name Manola, in turn a diminutive of Manuela. Notable people with the name include:
Manolita Arriola (1919–2004), Mexican singer and actress Manolita Cinco (born 1932), Filipina hurdler Manolita Piña (1883–1994), Spanish-Uruguayan pianist and painter Manolita Saval (1914–2001), Spanish actress and singer
See also Manola Manolito